Properties |
Information |
PhytoCAT-ID |
PhytoCAT-1185 |
Phytochemical name or plant extracts |
Scutebata A |
PMID |
30444060 |
Literature evidence |
Scutebata A (14) showed significant cytotoxic activities against four tested tumor cells with IC50 values of 4.57, 7.68, 5.31, and 6.23 μm, respectively, which indicated that it might be a potential chemotherapeutic agent. © 2019 Wiley-VHCA AG, Zurich, Switzerland. |
IUPAC name |
[(1R,2S,3R,4S,4aS,8aR)-4-[(1S)-1-acetyloxy-2-(4-hydroxy-5-oxo-2H-furan-3-yl)ethyl]-2-benzoyloxy-3-hydroxy-3,4,8,8a-tetramethyl-2,4a,5,6-tetrahydro-1H-naphthalen-1-yl] benzoate |
Phytochemicals’ class or type of plant extracts |
Diterpenoid |
Source of phytochemicals or plant Extracts |
Scutellaria barbata |
|
Geographical availability |
Assam, Bangladesh, China South-Central, China Southeast, East Himalaya, Japan, Korea, Laos, Myanmar, Nepal, Taiwan, Thailand, Vietnam, West Himalaya |
Plant parts |
Whole plant |
Other cancers |
Breast cancer, Colon cancer, Liver cancer |
Target gene or protein |
NA |
Gene or Protein evidence |
NA |
Target pathways |
NA |
IC50 |
7.68±0.06 μm against MCF-7 |
Potency |
Scutebata A (14) showed significant cytotoxic activities against four tested tumor cells with IC50 values of 4.57, 7.68, 5.31, and 6.23 μm, respectively, which indicated that it might be a potential chemotherapeutic agent. |
Cell line/ mice model |
MCF-7, LoVo, SMMC-7721, HCT-116 |
Additional information |
NA |
PubChem ID |
46183384 |
Additional PMIDs |
30449170 |
Additional sources of information |
https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:458159-1 |
Safety |
NA |