Phytochemical Name : Scutebata A

Properties Information
PhytoCAT-ID PhytoCAT-1185
Phytochemical name or plant extracts Scutebata A
PMID 30444060
Literature evidence Scutebata A (14) showed significant cytotoxic activities against four tested tumor cells with IC50 values of 4.57, 7.68, 5.31, and 6.23 μm, respectively, which indicated that it might be a potential chemotherapeutic agent. © 2019 Wiley-VHCA AG, Zurich, Switzerland.
IUPAC name [(1R,2S,3R,4S,4aS,8aR)-4-[(1S)-1-acetyloxy-2-(4-hydroxy-5-oxo-2H-furan-3-yl)ethyl]-2-benzoyloxy-3-hydroxy-3,4,8,8a-tetramethyl-2,4a,5,6-tetrahydro-1H-naphthalen-1-yl] benzoate
Phytochemicals’ class or type of plant extracts Diterpenoid
Source of phytochemicals or plant Extracts Scutellaria barbata
Geographical availability Assam, Bangladesh, China South-Central, China Southeast, East Himalaya, Japan, Korea, Laos, Myanmar, Nepal, Taiwan, Thailand, Vietnam, West Himalaya
Plant parts Whole plant
Other cancers Breast cancer, Colon cancer, Liver cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 7.68±0.06 μm against MCF-7
Potency Scutebata A (14) showed significant cytotoxic activities against four tested tumor cells with IC50 values of 4.57, 7.68, 5.31, and 6.23 μm, respectively, which indicated that it might be a potential chemotherapeutic agent.
Cell line/ mice model MCF-7, LoVo, SMMC-7721, HCT-116
Additional information  NA
PubChem ID 46183384
Additional PMIDs 30449170
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:458159-1
Safety NA