| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-574 | |
| Phytochemical name or plant extracts | Schisanol | |
| PMID | 27620660 | |
| Literature evidence | The cytotoxicity of the extracts, fractions and pure compounds were evaluated for their abilities to inhibit the proliferation of breast cancer cells MCF7 and tongue cancer cells CAL27. | |
| IUPAC name | (2R)-2-[(1S)-1-[(3S,5R,8S,10S,13R,14S,17R)-3-hydroxy-4,4,10,13,14-pentamethyl-2,3,5,6,7,8,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]ethyl]-5-methyl-2,3-dihydropyran-6-one | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Schisandra viridis | |
| Geographical availability | China South-Central, China Southeast | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer, Tongue cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 10.6 ± 0.5 μg/mL against MCF-7 | |
| Potency | Triterpenoid 6 were 10 times more active with IC50 values of 14.5, 13.4, 10.6µg/mL against MCF7, and 21.2, 17.9, 11.7µg/mL against CAL27, respectively. | |
| Cell line/ mice model | MCF-7, CAL27, HEK293 | |
| Additional information | NA | |
| PubChem ID | 135397241 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:555082-1 | |
| Safety | NA |