| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-731 | |
| Phytochemical name or plant extracts | Schinus molle essential oil | |
| PMID | 19023816 | |
| Literature evidence | Chemical composition of Schinus molle essential oil and its cytotoxic activity on tumour cell lines. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Essential oil | |
| Source of phytochemicals or plant Extracts | Schinus molle | |
| Geographical availability | Argentina Northeast, Brazil South, Chile North, Paraguay, Peru, Uruguay | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer, Leukemia | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | The antioxidant activity showed an IC(50) of 36.3 μg mL(-1). | |
| Potency | The essential oil did not induce significant necrosis up to 200 microg mL(-1), which together with the former results indicate that apoptosis is the main mechanism of toxicity induced by S. molle essential oil in this cell line. | |
| Cell line/ mice model | EMT-6, K562 | |
| Additional information | In conclusion, the essential oil tested was weak antioxidant and induced cytotoxicity in different cell types by a mechanism related to apoptosis. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:71044-1 | |
| Safety | NA |