Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1829 | |
Phytochemical name or plant extracts | Saussurea lappa extract(ESL) | |
PMID | 24885456 | |
Literature evidence | Thus, ESL has potential for controlling breast cancer invasiveness in vitro. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Extract | |
Source of phytochemicals or plant Extracts | Saussurea lappa | |
Geographical availability | China North-Central, China South-Central, China Southeast, East Himalaya, Hainan, Inner Mongolia, Manchuria, Nepal, Pakistan, Qinghai, Tibet, Vietnam, West Himalaya, Xinjiang | |
Plant parts | NA | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | These results indicate that ELS-mediated inhibition of TPA-induced MMP-9 expression and cell invasion involves the suppression of NF-κB pathway in MCF-7 cells. | |
IC50 | NA | |
Potency | Thus, ESL has potential for controlling breast cancer invasiveness in vitro. | |
Cell line/ mice model | MCF-7 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:242389-1 | |
Safety | NA |