Phytochemical Name : Saussurea lappa extract(ESL)

Properties Information
PhytoCAT-ID PhytoCAT-1829
Phytochemical name or plant extracts Saussurea lappa extract(ESL)
PMID 24885456
Literature evidence Thus, ESL has potential for controlling breast cancer invasiveness in vitro.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Extract
Source of phytochemicals or plant Extracts Saussurea lappa
Geographical availability China North-Central, China South-Central, China Southeast, East Himalaya, Hainan, Inner Mongolia, Manchuria, Nepal, Pakistan, Qinghai, Tibet, Vietnam, West Himalaya, Xinjiang
Plant parts NA
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways These results indicate that ELS-mediated inhibition of TPA-induced MMP-9 expression and cell invasion involves the suppression of NF-κB pathway in MCF-7 cells.
IC50 NA
Potency Thus, ESL has potential for controlling breast cancer invasiveness in vitro.
Cell line/ mice model MCF-7
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:242389-1
Safety NA