| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-795 | |
| Phytochemical name or plant extracts | Sauromatum giganteum extract | |
| PMID | 25605148 | |
| Literature evidence | Ethanol but not aqueous extracts of tubers of Sauromatum Giganteum(Engl.) Cusimano and Hett inhibit cancer cell proliferation. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Alcohol and Aqueous extract | |
| Source of phytochemicals or plant Extracts | Sauromatum giganteum | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Manchuria, Tibet | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Liver cancer, Stomach cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | An ethanol extract of Sauromatum giganteum(Engl.) Cusimano and Hett inhibited the proliferation of SMMC-7721, SGC-7901 and MCF-7 cells, which supports the use of alcoholic but not aqueous extracts for control of sensive cancers, which might include hepatocarcinoma, gastric cancer and breast cancer. | |
| Cell line/ mice model | MCF-7, SMMC-7721, SGC-7901 | |
| Additional information | Cancer cells treated with medium supplemented with 10%, 20%, 40% serum(v/v) containing ethanol extract had a decline in viability, with inhibition rates of 7.69%, 21.8%, 41.9% in MCF-7 cells, 42.8%, 48.1%, 51.8% in SGC-7901 cells, 44.1%, 49.2%, 53.7% in SMMC-7721 cells, 6.8%, 15.2%, 39.8% in HepG2 cells, 7.57%, 16.3%, 36.2% in HeLa cells, 6.24%, 12.5%, 27.4% in A549 cells, and 7.20%, 17.5%, 31.3% in MDA-MB-231 cells, respectively. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:77104738-1 | |
| Safety | NA |