| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1363 | |
| Phytochemical name or plant extracts | Satureja khuzestanica total extract | |
| PMID | 29755565 | |
| Literature evidence | In conclusion, satureja extract has a potential anti-cancer property against human breast cancer cells and its combination with chemotherapeutic agent vincristine may induce cell death effectively and be a potent modality to treat this type of cancer. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Satureja khuzestanica | |
| Geographical availability | Iran | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | Bax, Bcl-2, Cyclin D1 | |
| Gene or Protein evidence | Our study showed that SKE at doses of 150 and 200 µg/mLcould increase the ratio of Bax/Bcl-2 proteins expression. In addition, cyclin D1 expression was significantly decreased in the SKE-treated cells. | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | NA | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:986138-1 | |
| Safety | NA |