Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1624 | |
Phytochemical name or plant extracts | Sargassum angustifolium extract | |
PMID | 27499794 | |
Literature evidence | Cytotoxic results showed that all species could inhibit cell growth effectively, especially MCF-7 cell line (IC50 = 67.3, 56.9, 60.4 for S. oligocystum, S. angustifolium and S. boveanum respectively). | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Seaweed | |
Source of phytochemicals or plant Extracts | Sargassum angustifolium | |
Geographical availability | Persian Gulf | |
Plant parts | NA | |
Other cancers | Breast cancer, Colorectal cancer, Cervical cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 67.3 μg/ml against MCF-7 | |
Potency | Sargassum angustifolium had the highest content of total phenolics (0.061 mg/g) and showed the highest antioxidant activity (IC50 = 0.231). | |
Cell line/ mice model | HT-29, HeLa and MCF-7 | |
Additional information | Considerable phytochemicals and moderate cytotoxic activity of S. angustifolium, S. oligocystum and S. boveanum make them appropriate candidate for further studies and identification of their bioactive principles. | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | NA | |
Safety | NA |