Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-2105 | |
Phytochemical name or plant extracts | Salvia atropatana extract | |
PMID | 32936354 | |
Literature evidence | Owing to its numerous biological activities, Salvia species could be represented as a natural potential source against several cancer cell lines. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Petroleum ether fraction, Ethyl acetate fraction, n butanol fraction, Aqueous extract, Methanolic extract | |
Source of phytochemicals or plant Extracts | Salvia atropatana | |
Geographical availability | Iran, Iraq, Turkey, Turkmenistan | |
Plant parts | Root | |
Other cancers | Breast cancer, Prostate cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | Petroleum ether fraction - 26.15 ± 1.4 μg/ml against MCF-7 and 66.23 ± 6.7 μg/ml against MDA-MB-231 Ethyl acetate fraction - 49.71 ± 5.7 μg/ml against MCF-7 and 65.69 ± 3.8 μg/ml against MDA-MB-231 n butanol fraction - > 200 μg/ml against MCF-7 and 87.66 ± 8.4 μg/ml against MDA-MB-231 Aqueous extract - > 200 μg/ml against MCF-7 and 151.90 ± 10.6 μg/ml against MDA-MB-231 Methanolic extract - 69.04 ± 2.8 μg/ml against MCF-7 and 72.45 ± 5.1 μg/ml against MDA-MB-231 | |
Potency | NA | |
Cell line/ mice model | PC3, MCF-7, MDA-MB-231 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:455705-1 | |
Safety | NA |