| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1702 | |
| Phytochemical name or plant extracts | Salvia africana extract | |
| PMID | 31783509 | |
| Literature evidence | S. africana aqueous extract exhibited high antioxidant potential in four methods, namely the DPPH• (2,2-diphenyl-1-picrylhydrazyl) scavenging ability, iron-reducing power, inhibition of β-carotene bleaching and of thiobarbituric acid reactive substances (TBARS), for which EC50 values were equal or only 1.3-3.1 higher than those of the standard compounds. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Aqueous extract | |
| Source of phytochemicals or plant Extracts | Salvia africana | |
| Geographical availability | Cape Provinces | |
| Plant parts | Leaves and root | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | GI50 = 61.3 ± 9.8 μg/mL against MCF-7 | |
| Cell line/ mice model | HepG2, HeLa, MCF-7 | |
| Additional information | The three sage aqueous extracts of(Salvia africana, Salvia officinalis 'Icterina' and Savia mexicana) showed promising cytotoxic effect towards hepatocellular HepG2, cervical HeLa, and breast carcinoma cells MCF-7 | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:455585-1 | |
| Safety | NA |