| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2042 | |
| Phytochemical name or plant extracts | Saikosaponin-b4 | |
| PMID | 26259802 | |
| Literature evidence | Among them, compound 20 was isolated from the natural product for the first time. | |
| IUPAC name | (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,4R,4aR,6aR,6bS,8R,8aS,12aS,14R,14aR,14bS)-8-hydroxy-4,8a-bis(hydroxymethyl)-14-methoxy-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl]oxy]-3,5-dihydroxy-6-methyloxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Bupleurum chinense | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Inner Mongolia, Korea, Manchuria, Vietnam | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Liver cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | >50 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | A549, HepG2, Hep3B, BCap-37, MCF-7 | |
| Additional information | NA | |
| PubChem ID | 21637636 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:839099-1 | |
| Safety | NA |