Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-2056 | |
Phytochemical name or plant extracts | Saikosaponin-b1 | |
PMID | 26259802 | |
Literature evidence | Among them, compound 20 was isolated from the natural product for the first time. | |
IUPAC name | (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-2-[[(3S,4R,4aR,6aR,6bS,8S,8aS,14bS)-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,14a-dodecahydropicen-3-yl]oxy]-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-6-methyloxane-3,4,5-triol | |
Phytochemicals’ class or type of plant extracts | Triterpenoid | |
Source of phytochemicals or plant Extracts | Bupleurum chinense | |
Geographical availability | China North-Central, China South-Central, China Southeast, Inner Mongolia, Korea, Manchuria, Vietnam | |
Plant parts | Root | |
Other cancers | Breast cancer, Liver cancer, Lung cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | >50 μM against MCF-7 | |
Potency | NA | |
Cell line/ mice model | A549, HepG2, Hep3B, BCap-37, MCF-7 | |
Additional information | NA | |
PubChem ID | 3085144 | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:839099-1 | |
Safety | NA |