| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2047 | |
| Phytochemical name or plant extracts | Saikosaponin-E | |
| PMID | 26259802 | |
| Literature evidence | Among them, compound 20 was isolated from the natural product for the first time. | |
| IUPAC name | (2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-3,5-dihydroxy-2-[[(1S,2S,4S,5R,8R,10S,13S,14R,17S,18R)-2-hydroxy-4,5,9,9,13,20,20-heptamethyl-24-oxahexacyclo[15.5.2.01,18.04,17.05,14.08,13]tetracos-15-en-10-yl]oxy]-6-methyloxan-4-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Bupleurum chinense | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Inner Mongolia, Korea, Manchuria, Vietnam | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Liver cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 21.29 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | A549, HepG2, Hep3B, BCap-37, MCF-7 | |
| Additional information | NA | |
| PubChem ID | 21637632 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:839099-1 | |
| Safety | NA |