| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1087 | |
| Phytochemical name or plant extracts | Saffron extract | |
| PMID | 19457443 | |
| Literature evidence | Thus saffron exerts proapoptotic effects in a breast cancer-derived cell line and could be considered as a potential chemotherapeutic agent in breast cancer. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Crocus sativus | |
| Geographical availability | Greece | |
| Plant parts | Dry stigmas | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | Saffron-induced apoptosis could be inhibited by pan-caspase inhibitors, indicating caspase-dependent pathway was induced by saffron in MCF-7 cells. | |
| IC50 | 400+/-18.5 μg/ml against MCF-7 | |
| Potency | Thus saffron exerts proapoptotic effects in a breast cancer-derived cell line and could be considered as a potential chemotherapeutic agent in breast cancer. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | Saffron, a commonly-used spice and food additive, is known for its anti-cancer and anti-tumor properties | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:436688-1 | |
| Safety | NA |