| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1598 | |
| Phytochemical name or plant extracts | Rukamtenol | |
| PMID | 33258382 | |
| Literature evidence | Rukamtenol, flacourtin, and 3,4,5-trimethoxyphenyl β-D-glucopyranoside were tested for cytotoxic activity toward three MDA-MB-231, HepG2, and RD cancer cell lines. | |
| IUPAC name | (4R,5S)-4-hydroxy-2-oxaspiro[4.4]non-6-en-3-one | |
| Phytochemicals’ class or type of plant extracts | NA | |
| Source of phytochemicals or plant Extracts | Flacourtia rukam Zoll & Moritzi | |
| Geographical availability | Borneo, Caroline Is., Fiji, Jawa, Lesser Sunda Is., Malaya, Maluku, New Guinea, Nicobar Is., Niue, Philippines, Samoa, Solomon Is., Sulawesi, Sumatera, Tonga, Vanuatu, Wallis-Futuna Is. | |
| Plant parts | Stem | |
| Other cancers | Breast cancer, Liver Cancer, Myosarcoma | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | >100 µM against MDA-MB-231 | |
| Potency | Rukamtenol, flacourtin, and 3,4,5-trimethoxyphenyl β-D-glucopyranoside were tested for cytotoxic activity toward three MDA-MB-231, HepG2, and RD cancer cell lines. However, they failed to reveal any activity (IC50 > 100 ?M) on these cell lines. | |
| Cell line/ mice model | MDA-MB-231, HepG2, and RD | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:111681-1 | |
| Safety | NA |