Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-766 | |
Phytochemical name or plant extracts | Rubus crategifolius extract | |
PMID | 10976580 | |
Literature evidence | Furthermore, the methanol extract and its W-M fraction inhibited the activity of the topoisomerase I enzyme in the relaxation assay. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Methanolic extract | |
Source of phytochemicals or plant Extracts | Rubus crategifolius | |
Geographical availability | Buryatiya, China North-Central, Inner Mongolia, Japan, Korea, Manchuria, Primorye | |
Plant parts | Root | |
Other cancers | Breast cancer | |
Target gene or protein | Topoisomerase I | |
Gene or Protein evidence | Furthermore, the methanol extract and its W-M fraction inhibited the activity of the topoisomerase I enzyme in the relaxation assay. | |
Target pathways | NA | |
IC50 | NA | |
Potency | NA | |
Cell line/ mice model | MCF-7 | |
Additional information | From these results, their W-M fraction as well as methanol extract of R. crategifolius roots are necessary for further studies as a potent inhibitor of the growth of cancer cells. | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:736083-1 | |
Safety | NA |