| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1462 | |
| Phytochemical name or plant extracts | Rostratamin | |
| PMID | 25451793 | |
| Literature evidence | Compound 1 revealed significant cytotoxicities on HL-60 (IC50 6.72μM) and MCF-7 (IC50 2.89μM), and compounds 14 and 15 also revealed strong inhibitory activities against K-562 (IC50 6.72μM) or MCF-7 (IC50 2.49μM), respectively. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Pregnane sapogenin | |
| Source of phytochemicals or plant Extracts | Cynanchum wilfordii | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Japan, Korea, Manchuria, Primorye, Tibet | |
| Plant parts | Root | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 2.49 µM against MCF-7 | |
| Potency | compounds 14 and 15 also revealed strong inhibitory activities against K-562 (IC50 6.72µM) or MCF-7 (IC50 2.49µM), respectively. Compound 15 is Rostratamin. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:96697-1 | |
| Safety | NA |