| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1173 | |
| Phytochemical name or plant extracts | Rhus verniciflua Stokes extract (PPEF) | |
| PMID | 19606519 | |
| Literature evidence | Therefore, PPEF may have a significant potential as an organ-specific anti-cancer agent. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Phenolic-rich ethyl-acetate fraction | |
| Source of phytochemicals or plant Extracts | Rhus verniciflua | |
| Geographical availability | China North-Central, China South-Central, China Southeast, East Himalaya, Korea, Manchuria, Nepal, Pakistan, Tibet, West Himalaya | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Stomach cancer, Lung cancer, Colon cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 150 µg/ml against MDA-MB-231 145 µg/ml against MCF-7 100 µg/ml against SKBR-3 | |
| Potency | This fraction contains a number of phenolic compounds, and this phenolic-rich EtOAC fraction was particularly effective against gastric and breast cancer cells. | |
| Cell line/ mice model | MCF-7, MDA-MB-231, SKBR-3, AGS, SNU-668, SNU-638, A549, NCI-H157, HCT116, HepG2 | |
| Additional information | The results showed that PPEF induces apoptosis only in gastric and breast cancer cell lines, but not in lung, colon or liver cancer cell lines. Therefore, PPEF may have a significant potential as an organ-specific anti-cancer agent. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:70958-1 | |
| Safety | NA |