Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-924 | |
Phytochemical name or plant extracts | Rhoifolin (RFL) | |
PMID | 34649211 | |
Literature evidence | CONCLUSION: RFL shows anti-motile properties on breast cancer cells, which is due to its potential to downregulate Podocalyxin-Ezrin interaction during Epithelial Mesenchymal Transition. | |
IUPAC name | 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one | |
Phytochemicals’ class or type of plant extracts | Flavonoid | |
Source of phytochemicals or plant Extracts | Callicarpa nudiflora | |
Geographical availability | Bangladesh, China Southeast, Hainan, India, Malaya, Myanmar, Sri Lanka, Vietnam | |
Plant parts | NA | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | NA | |
Potency | RFL shows anti-motile properties on breast cancer cells, which is due to its potential to downregulate Podocalyxin-Ezrin interaction during Epithelial Mesenchymal Transition. | |
Cell line/ mice model | MDA-MB-231 | |
Additional information | NA | |
PubChem ID | 5282150 | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:861416-1 | |
Safety | NA |