Phytochemical Name : Rhoifolin (RFL)

Properties Information
PhytoCAT-ID PhytoCAT-924
Phytochemical name or plant extracts Rhoifolin (RFL)
PMID 34649211
Literature evidence CONCLUSION: RFL shows anti-motile properties on breast cancer cells, which is due to its potential to downregulate Podocalyxin-Ezrin interaction during Epithelial Mesenchymal Transition.
IUPAC name 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one
Phytochemicals’ class or type of plant extracts Flavonoid
Source of phytochemicals or plant Extracts Callicarpa nudiflora
Geographical availability Bangladesh, China Southeast, Hainan, India, Malaya, Myanmar, Sri Lanka, Vietnam
Plant parts NA
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 NA
Potency RFL shows anti-motile properties on breast cancer cells, which is due to its potential to downregulate Podocalyxin-Ezrin interaction during Epithelial Mesenchymal Transition.
Cell line/ mice model MDA-MB-231
Additional information  NA
PubChem ID 5282150
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:861416-1
Safety NA