Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1232 | |
Phytochemical name or plant extracts | Rhinacanthin A | |
PMID | 29154868 | |
Literature evidence | Rhinacanthin S (1) exhibited acetylcholinesterase inhibition activity with a % inhibition value of 48.04±3.25. | |
IUPAC name | (3R)-3-hydroxy-2,2-dimethyl-3,4-dihydrobenzo[g]chromene-5,10-dione | |
Phytochemicals’ class or type of plant extracts | Quinone | |
Source of phytochemicals or plant Extracts | Rhinacanthus nasutus | |
Geographical availability | Bangladesh, Cambodia, India, Laos, Malaya, Myanmar, Philippines, Sri Lanka, Thailand, Vietnam | |
Plant parts | Leaves | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 8.79 µM against MCF-7 | |
Potency | The known rhinacanthin A (5) showed cytotoxicity against a MCF-7 cell line with an IC50 value of 8.79 µM. | |
Cell line/ mice model | MCF-7 | |
Additional information | NA | |
PubChem ID | 44245542 | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:53554-1 | |
Safety | NA |