Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1757 | |
Phytochemical name or plant extracts | Rheum emodi extract | |
PMID | 21875266 | |
Literature evidence | The ability of the extracts to induce apoptosis in MDA-MB-435S (human breast carcinoma), Hep3B (human hepatocellular carcinoma) and PC-3 (human prostate cancer) cell lines were tested by ELISA to detect cellular DNA fragmentation. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Extract | |
Source of phytochemicals or plant Extracts | Rheum emodi | |
Geographical availability | Nepal, Pakistan, Tibet, West Himalaya | |
Plant parts | Rhizome | |
Other cancers | Breast cancer, Liver cancer, Prostate cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | NA | |
Potency | The strategy employed in this study, to induce apoptosis in the tumor cells, could be a potential target of therapeutic intervention of cancers. | |
Cell line/ mice model | MDA-MB-435S, Hep3B, PC-3 | |
Additional information | he study concludes that R. emodi possess anticancer metabolites that can be isolated and used as precursors in development of anticancer drugs. | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:696733-1 | |
Safety | NA |