Phytochemical Name : Rheum emodi extract

Properties Information
PhytoCAT-ID PhytoCAT-1757
Phytochemical name or plant extracts Rheum emodi extract
PMID 21875266
Literature evidence The ability of the extracts to induce apoptosis in MDA-MB-435S (human breast carcinoma), Hep3B (human hepatocellular carcinoma) and PC-3 (human prostate cancer) cell lines were tested by ELISA to detect cellular DNA fragmentation.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Extract
Source of phytochemicals or plant Extracts Rheum emodi
Geographical availability Nepal, Pakistan, Tibet, West Himalaya
Plant parts Rhizome
Other cancers Breast cancer, Liver cancer, Prostate cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 NA
Potency The strategy employed in this study, to induce apoptosis in the tumor cells, could be a potential target of therapeutic intervention of cancers.
Cell line/ mice model MDA-MB-435S, Hep3B, PC-3
Additional information  he study concludes that R. emodi possess anticancer metabolites that can be isolated and used as precursors in development of anticancer drugs.
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:696733-1
Safety NA