| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1568 | |
| Phytochemical name or plant extracts | Red grape wine extract (RWPF) | |
| PMID | 17002470 | |
| Literature evidence | Polyphenolic components such as flavonoids are strong antioxidants and induce the expression of several xenobiotic-detoxifying enzymes. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Red grape wine polyphenol fraction | |
| Source of phytochemicals or plant Extracts | Vitis palmata | |
| Geographical availability | Alabama, Arkansas, Florida, Georgia, Illinois, Indiana, Kentucky, Louisiana, Mississippi, Missouri, Oklahoma, Tennessee, Texas | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | This property could further be developed toward breast cancer prevention strategies either independently or in conjunction with conventional prevention therapies where a positive drug-nutrient interaction can be demonstrated. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | MCF-7 cells treated with the red wine polyphenol fraction (RWPF) showed swelling of endoplasmic reticulum, dissolution of the nucleus, and loss of plasma membrane integrity as well as reduced mitochondrial membrane potential. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:311399-2 | |
| Safety | NA |