| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1812 | |
| Phytochemical name or plant extracts | Radix ranunculus ternati polysaccharides | |
| PMID | 24311864 | |
| Literature evidence | FCM showed that the polysaccharides can induce apoptosis. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Polysaccharide | |
| Source of phytochemicals or plant Extracts | Ranunculus ternatus Thunb | |
| Geographical availability | Albania, Aleutian Is., Altay, Amur, Austria, Baltic States, Belarus, Belgium, Bulgaria, Central European Rus, Chita, Corse, Czechoslovakia, Denmark, East European Russia, Finland, France, Føroyar, Germany, Great Britain, Greece, Greenland, Hungary, Iceland, Ireland, Italy, Kamchatka, Kazakhstan, Khabarovsk, Kirgizstan, Krasnoyarsk, Magadan, Mongolia, Netherlands, North Caucasus, North European Russi, Northwest European R, Norway, Poland, Primorye, Romania, Sakhalin, South European Russi, Spain, Sweden, Switzerland, Transcaucasus, Tunisia, Tuva, Ukraine, West Siberia, Yugoslavia | |
| Plant parts | Root tuber | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | FCM showed that the polysaccharides can induce apoptosis. In addition, it can also enhance NK cell activity. Radix ranunculus ternati polysaccharides have a relatively good in-vitro anti-breast cancer activity. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | Compared with the blank control group, the percentage of G2/M phase cells increased (blank control group 3.53%, Radix ranunculus ternati polysaccharides group 12.54%), the percentage of G0/G1 phase cells declined (blank control group 67.51%, Radix ranunculus ternati polysaccharides group, 47.35%). | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:713963-1 | |
| Safety | NA |