| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2081 | |
| Phytochemical name or plant extracts | Quercus macrocarpa extract | |
| PMID | 31717611 | |
| Literature evidence | Targeted profiling of polyphenols in trees may reveal valuable sources of natural compounds with major applications in pharmacology and disease control. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Quercus macrocarpa | |
| Geographical availability | Alabama, Alberta, Arkansas, Connecticut, Illinois, Indiana, Iowa, Kansas, Kentucky, Louisiana, Maine, Manitoba, Maryland, Massachusetts, Michigan, Minnesota, Missouri, Montana, Nebraska, New Brunswick, New York, North Dakota, Ohio, Oklahoma, Ontario, Pennsylvania, Québec, Saskatchewan, South Dakota, Tennessee, Texas, Vermont, Virginia, West Virginia, Wisconsin, Wyoming | |
| Plant parts | Bark | |
| Other cancers | Breast cancer, Cervical cancer, Colorectal cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 43.54 ± 1.3 µg/mL against MCF-7 | |
| Potency | There were also noticeable anticancer activities against MCF-7, HeLa, Jurkat, and HT-29 cell lines, with the highest anticancer activity in the extracts of Q. robur. | |
| Cell line/ mice model | MCF-7, HeLa, Jurkat, HT-29 | |
| Additional information | This is the first study that reveals not only novel sources of important polyphenols (e.g. ellagic acid) in Q. robur, Q. macrocarpa and Q. acutissima bark but also their anticancer activities against diverse cancer cell lines. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:30014114-2 | |
| Safety | NA |