| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2113 | |
| Phytochemical name or plant extracts | Quercus infectoria extract | |
| PMID | 32963712 | |
| Literature evidence | More researches were conducted to search for selective cytotoxic agent of plant natural product on cancer cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethyl acetate extract | |
| Source of phytochemicals or plant Extracts | Quercus infectoria | |
| Geographical availability | Cyprus, East Aegean Is., Greece, Iran, Iraq, Lebanon-Syria, Palestine, Transcaucasus, Turkey, Kota Bharu, Kelantan, Malaysia | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Liver cancer, Cervical cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 20.5 ± 1.23 μg/mL against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MDA-MB-231, HeLa, Hep G2, L929 | |
| Additional information | QIEA extract exhibited the most potent cytotoxic activity against HeLa cells with (IC50 value = 6.33 ± 0.33 μg/mL) and showed cytoselective property against L929 cells. DNA fragmentation revealed QIEA induced apoptosis in the treated cells. The richness of phytochemical constituents in QIEA extract might contribute to the potency of cytotoxic activity towards HeLa cells. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:296305-1 | |
| Safety | NA |