| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1042 | |
| Phytochemical name or plant extracts | Quercitrin | |
| PMID | 32101118 | |
| Literature evidence | Thus, our data suggest that phenolic compounds in A. tabularis extracts promote antioxidant activity, and furthermore, these extracts show numerous features that indicate potential for therapeutic development. | |
| IUPAC name | 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxychromen-4-one | |
| Phytochemicals’ class or type of plant extracts | Flavonoid | |
| Source of phytochemicals or plant Extracts | Mangifera pajang | |
| Geographical availability | Borneo | |
| Plant parts | Stem, Bark, Leaves | |
| Other cancers | Breast cancer, Cervical cancer, Colon cancer | |
| Target gene or protein | ABCG2 | |
| Gene or Protein evidence | Chrysoeriol, laricitrin, myricetin 3',4',5'-trimethylether, pinocembrin, quercitrin, tamarixetin, tricetin and tricetin 3',4',5'-trimethylether were also identified as novel flavonoid ABCG2 inhibitors. | |
| Target pathways | NA | |
| IC50 | 25.04 ± 0.72 μg/mL against MCF-7 | |
| Potency | In contrast, weak cytotoxic activities were shown by lupeol (7), lupenone (8) and quercitrin (12) with IC50 values of 25.02 ± 0.71 , 27.01 ± 0.34 and 25.04 ± 0.72 μg/mL respectively | |
| Cell line/ mice model | MCF-7, HeLa, HT-29 | |
| Additional information | Quercitrin and isoquercitrin both bound Fe2+ ions efficiently to give strong UV absorption around 600 nm | |
| PubChem ID | 5280459 | |
| Additional PMIDs | 29564971 25887035 29142406 33146032 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:69947-1 | |
| Safety | NA |