Properties | Information |
---|---|
PhytoCAT-ID | PhytoCAT-1822 |
Phytochemical name or plant extracts | Quercetin-4'-O-sulphate |
PMID | 24573487 |
Literature evidence | Methylation on ring-B of quercetin decreased the anti-proliferative effects, especially when the methylation occurred in position 3' (isorhamnetin), although methylated metabolites still showed significant anti-proliferative activity. |
IUPAC name | [2-hydroxy-4-(3,5,7-trihydroxy-4-oxochromen-2-yl)phenyl] hydrogen sulfate |
Phytochemicals’ class or type of plant extracts | Flavonoid |
Source of phytochemicals or plant Extracts | NA |
Geographical availability | NA |
Plant parts | NA |
Other cancers | Breast cancer, Colon cancer, Pancreatic cancer |
Target gene or protein | NA |
Gene or Protein evidence | NA |
Target pathways | NA |
IC50 | NA |
Potency | Sulphated metabolites were also tested and found to be inactive in most of the explored cell lines, although quercetin-4'-O-sulphate and epicatechin-3'-O-sulphate still showed some anti-proliferative activity on MCF-7 and Caco-2 cells, respectively. |
Cell line/ mice model | MCF-7, Caco-2, BxPC-3 |
Additional information | NA |
PubChem ID | NA |
Additional PMIDs | NA |
Additional sources of information | NA |
Safety | NA |