Phytochemical Name : Quercetin-4'-O-sulphate

Properties Information
PhytoCAT-ID PhytoCAT-1822
Phytochemical name or plant extracts Quercetin-4'-O-sulphate
PMID 24573487
Literature evidence Methylation on ring-B of quercetin decreased the anti-proliferative effects, especially when the methylation occurred in position 3' (isorhamnetin), although methylated metabolites still showed significant anti-proliferative activity.
IUPAC name [2-hydroxy-4-(3,5,7-trihydroxy-4-oxochromen-2-yl)phenyl] hydrogen sulfate
Phytochemicals’ class or type of plant extracts Flavonoid
Source of phytochemicals or plant Extracts NA
Geographical availability NA
Plant parts NA
Other cancers Breast cancer, Colon cancer, Pancreatic cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 NA
Potency Sulphated metabolites were also tested and found to be inactive in most of the explored cell lines, although quercetin-4'-O-sulphate and epicatechin-3'-O-sulphate still showed some anti-proliferative activity on MCF-7 and Caco-2 cells, respectively.
Cell line/ mice model MCF-7, Caco-2, BxPC-3
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information NA
Safety NA