Phytochemical Name : Punicalagin

Properties Information
PhytoCAT-ID PhytoCAT-569
Phytochemical name or plant extracts Punicalagin
PMID 25624761
Literature evidence Thus, pomegranate polyphenols are promising agents for nanochemoprevention of breast cancer.
IUPAC name (1R,35R,38R,55S)-6,7,8,11,12,23,24,27,28,29,37,43,44,45,48,49,50-heptadecahydroxy-2,14,21,33,36,39,54-heptaoxaundecacyclo[33.20.0.04,9.010,19.013,18.016,25.017,22.026,31.038,55.041,46.047,52]pentapentaconta-4,6,8,10,12,16,18,22,24,26,28,30,41,43,45,47,49,51-octadecaene-3,15,20,32,40,53-hexone
Phytochemicals’ class or type of plant extracts Tannin
Source of phytochemicals or plant Extracts Punica granatum
Geographical availability Afghanistan, Iran, Iraq, North Caucasus, Pakistan, Tadzhikistan, Transcaucasus, Turkey, Turkmenistan
Plant parts Fruits
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 40.9 μM against MCF-7 48.4 μM against Hs578T
Potency Thus, pomegranate polyphenols are promising agents for nanochemoprevention of breast cancer.
Cell line/ mice model MCF-7, Hs578T
Additional information  These data demonstrate that nanotechnology-enabled delivery of pomegranate polyphenols enhances their anticancer effects in breast cancer cells.
PubChem ID 44584733
Additional PMIDs 25624761 34414576 34444893
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:554129-1
Safety NA