Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-569 | |
Phytochemical name or plant extracts | Punicalagin | |
PMID | 25624761 | |
Literature evidence | Thus, pomegranate polyphenols are promising agents for nanochemoprevention of breast cancer. | |
IUPAC name | (1R,35R,38R,55S)-6,7,8,11,12,23,24,27,28,29,37,43,44,45,48,49,50-heptadecahydroxy-2,14,21,33,36,39,54-heptaoxaundecacyclo[33.20.0.04,9.010,19.013,18.016,25.017,22.026,31.038,55.041,46.047,52]pentapentaconta-4,6,8,10,12,16,18,22,24,26,28,30,41,43,45,47,49,51-octadecaene-3,15,20,32,40,53-hexone | |
Phytochemicals’ class or type of plant extracts | Tannin | |
Source of phytochemicals or plant Extracts | Punica granatum | |
Geographical availability | Afghanistan, Iran, Iraq, North Caucasus, Pakistan, Tadzhikistan, Transcaucasus, Turkey, Turkmenistan | |
Plant parts | Fruits | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 40.9 μM against MCF-7 48.4 μM against Hs578T | |
Potency | Thus, pomegranate polyphenols are promising agents for nanochemoprevention of breast cancer. | |
Cell line/ mice model | MCF-7, Hs578T | |
Additional information | These data demonstrate that nanotechnology-enabled delivery of pomegranate polyphenols enhances their anticancer effects in breast cancer cells. | |
PubChem ID | 44584733 | |
Additional PMIDs | 25624761 34414576 34444893 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:554129-1 | |
Safety | NA |