| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1738 | |
| Phytochemical name or plant extracts | Pterogynine (PGN) | |
| PMID | 20700682 | |
| Literature evidence | Alkaloids extracted from Pterogyne nitens induce apoptosis in malignant breast cell line. | |
| IUPAC name | 1,1-bis(3-methylbut-2-enyl)guanidine | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Pterogyne nitens | |
| Geographical availability | Argentina Northeast, Argentina Northwest, Bolivia, Brazil Northeast, Brazil South, Brazil Southeast, Brazil West-Central, Paraguay, Uruguay | |
| Plant parts | NA | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | This indicates that PGD is more cytotoxic than PGN for this time of treatment in ZR-7531 cell line. | |
| Cell line/ mice model | ZR-7530 | |
| Additional information | pterogynine and pterogynidine inhibit the proliferation of human breast cancer cells and induce cell death by apoptosis. The alkaloids, isolated from P. nitens, could be a good chemotherapeutic compounds against human breast cancer cells. | |
| PubChem ID | 45268797 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:516619-1 | |
| Safety | NA |