Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1935 | |
Phytochemical name or plant extracts | Pteris Quadriureta (PQ) extract | |
PMID | 30194562 | |
Literature evidence | Plant products with potential anticancer activities have become a vital source of novel agents in treating cancer. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Methanolic extract and gold nanoparticles | |
Source of phytochemicals or plant Extracts | Pteris Quadriureta | |
Geographical availability | Bangladesh, India, Sri Lanka | |
Plant parts | NA | |
Other cancers | Breast cancer | |
Target gene or protein | Bcl-2, Cyclin D2 | |
Gene or Protein evidence | By using docking analysis, we also showed that phytol and eicosapentaenoic acid present in ACV and PQ interact with Bcl2 and cyclin D1. | |
Target pathways | NA | |
IC50 | NA | |
Potency | These findings demonstrate that ACV and PQ possess anticancer activities by modulating proteins involved in cell cycle and apoptosis. ACV and PQ that effectively modulate various oncogenic molecules can be used as promising agent for cancer therapy. | |
Cell line/ mice model | MCF-7 and BT47 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:17215900-1 | |
Safety | NA |