| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-631 | |
| Phytochemical name or plant extracts | Psidium guajava essential oil | |
| PMID | 30462815 | |
| Literature evidence | Our results suggest that the essential oil of Psidium guajava L. has promising biological activities and can be considered a new source of bioactive compounds. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Essential oil | |
| Source of phytochemicals or plant Extracts | Psidium guajava | |
| Geographical availability | Argentina Northeast, Argentina Northwest, Bolivia, Brazil Northeast, Brazil South, Brazil Southeast, Brazil West-Central, Colombia, Ecuador, Paraguay, Peru, Venezuela | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer, Cervical cancer, Glioma | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 96.9 ± 8.4 μg/mL against MCF-7 | |
| Potency | The evidence from this study, the high amount of terpenes, known for their anticancer activity such as β-caryophyllene (16.1%), aromadendrene oxide (14.7%), δ-selinene (13.6%), selin-11-en-4α-ol (12.5%), α-humulene (11.9%), β-caryophyllene oxide (4.1%), and α-cadinol (1.6%) ( Table 1 ), suggests that P. guajava essential oil is a significant potential source of pure compounds with promising anticancer activity | |
| Cell line/ mice model | MCF-7, HeLa, M059J | |
| Additional information | PG-EO had moderate activity against Streptococcus mutans (MIC = 200 µg/mL), S. mitis (MIC = 200 µg/mL), S. sanguinis (MIC = 400 µg/mL), S. sobrinus (MIC = 100 µg/mL), and S. salivarius (MIC = 200 µg/mL). | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:600841-1 | |
| Safety | NA |