| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-729 | |
| Phytochemical name or plant extracts | Protoberberine | |
| PMID | 25023388 | |
| Literature evidence | A novel hollow fiber cell fishing procedure with high-performance liquid chromatography (HFCF-HPLC) was developed and used for rapid screening, fishing, and analysis of bioactive compounds from traditional Chinese medicines. | |
| IUPAC name | 5,6-dihydroisoquinolino[2,1-b]isoquinolin-7-ium | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Coptis chinensis | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Vietnam | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Gastric cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | NA | |
| Cell line/ mice model | MCF-7, MADB106, SGC7901 | |
| Additional information | Human breast cancer cell MCF7, mouse breast cancer cell MADB106, and gastric cancer cell SGC7901 were seeded on the internal surface of hollow fibers that were used to screen, fish, and analyze an antitumor-active protoberberine alkaloid group from Coptis chinensis decoction. | |
| PubChem ID | 114943 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:710313-1 | |
| Safety | NA |