| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1166 | |
| Phytochemical name or plant extracts | Prosopis juliflora extract | |
| PMID | 33192211 | |
| Literature evidence | In conclusion, P. juliflora ethyl acetate extracts have a potential anti-cancer effect against breast adenocarcinoma, hepatocellular carcinoma, and colorectal adenocarcinoma, and is enriched with anti-cancer constituents. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethyl acetate extract | |
| Source of phytochemicals or plant Extracts | Prosopis juliflora | |
| Geographical availability | Aruba, Bahamas, Colombia, Costa Rica, Cuba, Dominican Republic, El Salvador, Guatemala, Haiti, Honduras, Leeward Is., Mexico Central, Mexico Gulf, Mexico Northeast, Mexico Northwest, Mexico Southeast, Mexico Southwest, Netherlands Antilles, Nicaragua, Panamá, Peru, Venezuela, Venezuelan Antilles, Windward Is. | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer, Liver cancer, Colorectal cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 18.17 μg/ml against MCF-7 | |
| Potency | In conclusion, P. juliflora ethyl acetate extracts have a potential anti-cancer effect against breast adenocarcinoma, hepatocellular carcinoma, and colorectal adenocarcinoma, and is enriched with anti-cancer constituents. | |
| Cell line/ mice model | MCF-7, HepG2 , LS-174T | |
| Additional information | P. juliflora leaves exerted higher cytotoxic effect on MCF-7 rather than HepG2 and LS-174T showing antiproliferative effects in different pathways throughout the cell stages. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:1002432-2 | |
| Safety | NA |