| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2055 | |
| Phytochemical name or plant extracts | Prosaikogenin A | |
| PMID | 26259802 | |
| Literature evidence | Among them, compound 20 was isolated from the natural product for the first time. | |
| IUPAC name | (2R,3R,4S,5R,6R)-2-[[(3S,4R,4aR,6aR,6bS,8S,8aS,14aR,14bS)-8-hydroxy-4,8a-bis(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4a,5,6,7,8,9,10,12,14a-dodecahydropicen-3-yl]oxy]-6-methyloxane-3,4,5-triol | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Bupleurum chinense | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Inner Mongolia, Korea, Manchuria, Vietnam | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Liver cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 42.1 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | A549, HepG2, Hep3B, BCap-37, MCF-7 | |
| Additional information | Specially, compounds 1, 3–4, 6–9, 11–13, 16–18 and 20 possessed a much higher cytotoxic effect against the HepG2 cell line than 5-fluorouracil. Compound 18 is Prosaikogenin A | |
| PubChem ID | 10009004 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:839099-1 | |
| Safety | NA |