| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1203 | |
| Phytochemical name or plant extracts | Proanthocyanidin | |
| PMID | 28689063 | |
| Literature evidence | Altogether, these data suggest that UPAs are potential therapeutic agents for breast cancer. | |
| IUPAC name | (3R)-2-(3,5-dihydroxy-4-methoxyphenyl)-8-[(2R,3R,4R)-3,5,7-trihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-4-yl]-3,4-dihydro-2H-chromene-3,5,7-triol | |
| Phytochemicals’ class or type of plant extracts | Flavonoid | |
| Source of phytochemicals or plant Extracts | Uncaria rhynchophylla | |
| Geographical availability | China South-Central, China Southeast, Japan, Taiwan, Vietnam | |
| Plant parts | Medicinal parts | |
| Other cancers | Breast cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | A549, HS578T and HEK293, and did not have any effect on MCF-7. Proanthocyanidin A and 4’-O-methylepigallocatechin belong to the group of flavonoids and are known for their antioxidant properties and anti-proliferative effect in cancer cell line | |
| Cell line/ mice model | MCF-7, A549, HS578T and HEK293 | |
| Additional information | NA | |
| PubChem ID | 108065 | |
| Additional PMIDs | 25735761 17012779 20121190 21382271 16546280 20503473 26401377 28211563 10448908 33491801 24969892 12946404 15525446 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:768297-1 | |
| Safety | NA |