| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1789 | |
| Phytochemical name or plant extracts | Potentilla fulgens (PRE) extract | |
| PMID | 23023566 | |
| Literature evidence | The study was intended to determine the effectiveness in antitumor activity among kaempferol (KMP) as flavonoids, ellagic acid (ELA) as polyphenols and methanolic extract of the root of P. fulgens (PRE) in Ehrlich ascites tumour (EA) and MCF-7 cancer cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Potentilla fulgens | |
| Geographical availability | Assam | |
| Plant parts | Root | |
| Other cancers | Breast cancer | |
| Target gene or protein | PARP1, Survivin | |
| Gene or Protein evidence | This effect may be attributed to apoptotic cell death as confirmed by flow cytometric analysis and PARP1 proteolysis. Such induction of apoptosis was achieved by suppression of inhibitor of the apoptosis protein survivin. | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | NA | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:728125-1 | |
| Safety | NA |