| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2176 | |
| Phytochemical name or plant extracts | Porphyra dentata | |
| PMID | 24062783 | |
| Literature evidence | This sterol fraction in vitro significantly inhibited cell growth and induced apoptosis in 4T1 cancer cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Porphyra dentata | |
| Geographical availability | Asia | |
| Plant parts | Algae | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Porphyra dentata, an edible red macroalgae, is used as a folk medicine in Asia. This study evaluated in vitro and in vivo the protective effect of a sterol fraction from P. dentata against breast cancer linked to tumor-induced myeloid derived-suppressor cells (MDSCs). | |
| Cell line/ mice model | 4T1 cell-implanted tumor BALB/c mice | |
| Additional information | Therefore, the sterol fraction from P. dentata showed potential for protecting an organism from 4T1 cell-based tumor genesis. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | NA | |
| Safety | NA |