| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1499 | |
| Phytochemical name or plant extracts | Pomegranate whole seed ethanolic extract | |
| PMID | 25149014 | |
| Literature evidence | Due the presence of bioactive compounds and the remarkable antiproliferative activity, the use of PSEE as a value-added ingredient in formulations of products aimed to prevent diseases, especially cancer, could be promoted. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Punica granatum | |
| Geographical availability | Afghanistan, Iran, Iraq, North Caucasus, Pakistan, Tadzhikistan, Transcaucasus, Turkey, Turkmenistan | |
| Plant parts | Seeds | |
| Other cancers | Breast cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 9.6 µg/ml against MCF-7 | |
| Potency | PSEE showed a promising antiproliferative activity against hormone dependent prostate carcinoma LNCaP, with an IC50 value 3 times lower than the positive control vinblastine, and against human breast cancer cell lines (IC50=9.6 µg/ml). | |
| Cell line/ mice model | ACHN, A375, C32, MCF-7, LNCaP, HeLa, COR-L23, 142BR | |
| Additional information | Due the presence of bioactive compounds and the remarkable antiproliferative activity, the use of PSEE as a value-added ingredient in formulations of products aimed to prevent diseases, especially cancer, could be promoted. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:554129-1 | |
| Safety | NA |