| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2079 | |
| Phytochemical name or plant extracts | Polysaccharides from Taxus cuspidata | |
| PMID | 31412567 | |
| Literature evidence | Taxus cuspidata S. et Z. is an excellent natural source of bioactive polysaccharides and has various biological activities. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Polysaccharide (Pe1, Pe2, Pe3, Pe4) | |
| Source of phytochemicals or plant Extracts | Taxus cuspidata | |
| Geographical availability | China North-Central, Japan, Korea, Kuril Is., Manchuria, Primorye, Sakhalin | |
| Plant parts | Leaves and Branches | |
| Other cancers | Breast cancer, Liver cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Pe1 - 169.0 µg/mL against MCF-7 | |
| Potency | The four purified polysaccharides (Pe1, Pe2, Pe3, Pe4) from TCBL are mainly composed of arabinose, galactose, glucose, a small amount of xylose, and mannose. Pe1 had the highest antitumor capacity against MCF7 cells and HepG2 cells, with IC50 values of 169.0 and 132.0 µg·mL-1. | |
| Cell line/ mice model | MCF-7, HepG2 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:324379-2 | |
| Safety | NA |