| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-37 | |
| Phytochemical name or plant extracts | Pluchea dioscoridis essential oil | |
| PMID | 33807147 | |
| Literature evidence | The EOs of P. dioscoridis, E. bonariensis, and their mixture (1:1) exhibited significant inhibitory activity of the collagenase, elastase, hyaluronidase, and tyrosinase comparing with epigallocatechin gallate (EGCG) as a reference. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Essential oil | |
| Source of phytochemicals or plant Extracts | Pluchea dioscoridis | |
| Geographical availability | Angola, Botswana, Burundi, Chad, Djibouti, Egypt, Eritrea, Ethiopia, Gulf States, Iraq, Kenya, KwaZulu-Natal, Lebanon-Syria, Mozambique, Northern Provinces, Oman, Palestine, Saudi Arabia, Sinai, Somalia, Sudan, Swaziland, Tanzania, Uganda, Yemen, Zambia, Zimbabwe | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 37.3 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7, A-549 | |
| Additional information | The EOs of P. dioscoridis, E. bonariensis, and their mixture (1:1) exhibited significant inhibitory activity of the collagenase, elastase, hyaluronidase, and tyrosinase comparing with epigallocatechin gallate (EGCG) as a reference. The results of anti-aging showed that the activity of mixture (1:1) > P. dioscoridis > E. bonariensis against the four enzymes. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:109824-3 | |
| Safety | NA |