| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-663 | |
| Phytochemical name or plant extracts | Pistacia integerrima extract | |
| PMID | 23626397 | |
| Literature evidence | These findings reveal that the ethyl acetate and chloroform fractions of Pistacia integerrima are potent cytotoxic fractions, and could be an alternate candidate for the development of novel biologically active compounds. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Pistacia integerrima | |
| Geographical availability | Afghanistan, East Himalaya, India, Myanmar, Nepal, Pakistan, Transcaucasus, West Himalaya | |
| Plant parts | Stem | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 90.9 μg/ml against MCF-7 | |
| Potency | The crude extract of P. integerrima showed moderate cytotoxicity in a dose-dependent manner up to 100 μg/ml concentration with a maximum inhibition of 55.4±2% at this concentration | |
| Cell line/ mice model | MCF-7 | |
| Additional information | The ethyl acetate and chloroform fractions at a concentration of 200 μg/ml showed ~100 and 97.4% inhibition against Michigan Cancer Foundation-7 cell line, respectively. The crude methanol extract also showed good antitumour (IC50 125 ppm) activity, but weak antifungal activity. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:60476211-2 | |
| Safety | NA |