Phytochemical Name : Piscidinol A

Properties Information
PhytoCAT-ID PhytoCAT-600
Phytochemical name or plant extracts Piscidinol A
PMID 26320684
Literature evidence The antiplasmodial activities of the crude extracts and the isolated constituents against the D6 and W2 strains of Plasmodium falciparum were determined using the semiautomated micro dilution technique that measures the ability of the extracts to inhibit the incorporation of (G-(3)H, where G is guanine) hypoxanthine into the malaria parasite.
IUPAC name (5R,9R,10R,13S,14S,17S)-4,4,10,13,14-pentamethyl-17-[(2S,4R,5S)-4,5,6-trihydroxy-6-methylheptan-2-yl]-1,2,5,6,9,11,12,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
Phytochemicals’ class or type of plant extracts Protolimonoid
Source of phytochemicals or plant Extracts Turraea nilotica
Geographical availability Burundi, Ethiopia, Kenya, Malawi, Mozambique, Northern Provinces, Somalia, Sudan, Swaziland, Tanzania, Zambia, Zimbabwe
Plant parts Stem
Other cancers Breast cancer, Larynx cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 8.0±0.0 µg/mL against 4T1.
Potency NA
Cell line/ mice model 4T1, HEp2, Vero
Additional information  NA
PubChem ID 12004524
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:579805-1
Safety NA