| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1156 | |
| Phytochemical name or plant extracts | Pinus nigra Arn. bark extracts from Mokra gora (MG) and Tara mountains | |
| PMID | 33491801 | |
| Literature evidence | The antiproliferative activity of P. nigra bark is probably related to the ferulic acid content and its synergistic activity to caffeic acid and taxifolin. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanol extract | |
| Source of phytochemicals or plant Extracts | Pinus nigra | |
| Geographical availability | Albania, Algeria, Austria, Bulgaria, Corse, Cyprus, East Aegean Is., France, Greece, Italy, Krym, Morocco, North Caucasus, Romania, Spain, Turkey, Turkey-in-Europe, Yugoslavia | |
| Plant parts | Bark | |
| Other cancers | Breast cancer, Cervical cancer, Colorectal cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Mokra gora - 43.28 ± 6.35 μg/ml against MCF-7 Tara - 27.84 ± 6.65 μg/ml against MCF-7 | |
| Potency | The composition of the presented compounds could be related to promising antioxidant and antiproliferative efficacy of MG bark. | |
| Cell line/ mice model | MCF-7, HeLa,HT-29, MRC-5 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:677088-1 | |
| Safety | NA |