| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1234 | |
| Phytochemical name or plant extracts | Pinostilbene | |
| PMID | 31004704 | |
| Literature evidence | In addition, TMS activated the AHR more potently (EC50 in a reporter gene assay 2.0 μM) and induced AHR-mediated induction of cytochrome P450 1A1 (CYP1A1) activity (EC50 value of 0.7 μM) more than resveratrol and the other analogues tested. | |
| IUPAC name | 3-[(E)-2-(4-hydroxyphenyl)ethenyl]-5-methoxyphenol | |
| Phytochemicals’ class or type of plant extracts | Stilbenoid | |
| Source of phytochemicals or plant Extracts | Commiphora africana | |
| Geographical availability | Angola, Benin, Botswana, Burkina, Cameroon, Caprivi Strip, Chad, Djibouti, Eritrea, Ethiopia, Gambia, Ghana, Ivory Coast, Kenya, KwaZulu-Natal, Malawi, Mali, Mauritania, Mozambique, Namibia, Niger, Nigeria, Northern Provinces, Rwanda, Senegal, Somalia, Sudan, Swaziland, Tanzania, Togo, Uganda, Zambia, Zaïre, Zimbabwe | |
| Plant parts | Stem | |
| Other cancers | Breast cancer, Prostate cancer, Lung cancer, Liver cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 29.36 ± 0.12 µg/ml against MCF-7 | |
| Potency | In this study, we report the antiproliferative potentials of the extracts and isolated compounds of C. africana on four human carcinoma cells. These results validate the folklore use of C. africana in the treatment of cancer. | |
| Cell line/ mice model | MCF-7, A549, PC3, HepG2 | |
| Additional information | NA | |
| PubChem ID | 5473050 | |
| Additional PMIDs | 30346066 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:127576-1 | |
| Safety | NA |