| Properties | Information |
|---|---|
| PhytoCAT-ID | PhytoCAT-1904 |
| Phytochemical name or plant extracts | Pine honey |
| PMID | 28695656 |
| Literature evidence | In contrast, pine honey showed dramatically significant cytotoxicity only on the MDAMB 231 cells with a 1 µg/mL dose at the same time point (P = 0.018). |
| IUPAC name | NA |
| Phytochemicals’ class or type of plant extracts | Multifloral honey and Honeydew honey |
| Source of phytochemicals or plant Extracts | NA |
| Geographical availability | Istanbul,Turkey |
| Plant parts | NA |
| Other cancers | Breast cancer, Kidney cancer, Prostate cancer, Uterus cancer, Cervical cancer , Oral cancer |
| Target gene or protein | NA |
| Gene or Protein evidence | NA |
| Target pathways | NA |
| IC50 | 2.4 μg/mL against MCF-7 |
| Potency | In contrast, pine honey showed dramatically significant cytotoxicity only on MDAMB 231 with 1 mg/mL at the same time point (P = 0.018) |
| Cell line/ mice model | MCF-7, SKBR-3, MDA -MB - 231 |
| Additional information | Chestnut, cedar, and pine honey displayed a remarkably cytotoxic effect on breast cancer cell lines, MCF7, SKBR3, and even on the most aggressive MDAMB 231, representing the triple negative breast cancer, which lacks of targeted anticancer therapy. Several benefits of honey have been reported in recent years such as anti-inflammatory , antimicrobial , antimutagenic, antioxidant, and antitumoral effects. It was indicated that honey effects the promotion of apoptosis via regulation of subG1 phase in human colon cancer. |
| PubChem ID | NA |
| Additional PMIDs | NA |
| Additional sources of information | NA |
| Safety | NA |