Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1345 | |
Phytochemical name or plant extracts | Picrorhiza kurroa extracts | |
PMID | 21081148 | |
Literature evidence | The ability of the extracts to induce apoptosis was also investigated. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Methanolic extract, Aqueous extract | |
Source of phytochemicals or plant Extracts | Picrorhiza kurroa | |
Geographical availability | Pakistan, West Himalaya | |
Plant parts | Rhizome | |
Other cancers | Breast cancer, Prostate cancer, Liver cancer, Cervical cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | Aqueous extract - 100.81 ± 8.3 µg/mL against MDA-MB-435 Methanolic extract - 19.00 ± 5.2 µg/mL against MDA-MB-435 | |
Potency | NA | |
Cell line/ mice model | MCF-7, MDA-MB 231, HeLa, SiHa, Hep3B, PC-3, MDA-MB-435S | |
Additional information | The DCM fraction of P. kurroa displayed potent anticancer activity and can be further explored for the development of a potential candidate for cancer therapy. | |
PubChem ID | NA | |
Additional PMIDs | 31201865 26557675 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:808408-1 | |
Safety | NA |