| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1916 | |
| Phytochemical name or plant extracts | Phyllanthus amarus (PAM) extract | |
| PMID | 28930257 | |
| Literature evidence | The antioxidant activity of PAM extract was significantly higher (p < 0.05) than that of the PAW extract, PAM fractions, and phyllanthin (known as a major compound in the P. amarus). | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Phyllanthus amarus | |
| Geographical availability | Argentina Northeast, Aruba, Bahamas, Belize, Bolivia, Brazil North, Brazil Northeast, Brazil South, Brazil Southeast, Brazil West-Central, Cayman Is., Chile North, Colombia, Costa Rica, Cuba, Dominican Republic, Ecuador, El Salvador, French Guiana, Guatemala, Guyana, Haiti, Honduras, Jamaica, Leeward Is., Mexico Gulf, Mexico Southeast, Mexico Southwest, Netherlands Antilles, Nicaragua, Panamá, Paraguay, Peru, Puerto Rico, Southwest Caribbean, Suriname, Trinidad-Tobago, Turks-Caicos Is., Uruguay, Venezuela, Windward Is. | |
| Plant parts | Whole plant | |
| Other cancers | Breast cancer, Pancreatic cancer, Colon cancer, Ovarian cancer, Lung cancer, Skin cancer, Prostate cancer, Neuroblastoma, Glioma | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | The results achieved from this study reveal that the PA extracts are a potential source for the development of natural antioxidant products and/or novel anticancer drugs. | |
| Cell line/ mice model | MiaPaCa-2 , HT29, A2780, H460, A431, Du145, BE2-C , MCF-7, MCF-10A, U87, SJ-G2, SMA | |
| Additional information | Phyllanthus amarus (P. amarus) has been used as a medicinal plant for the prevention and treatment of chronic ailments such as diabetes, hepatitis, and cancer | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:326408-2 | |
| Safety | NA |