| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1455 | |
| Phytochemical name or plant extracts | Phlomis russeliana extract | |
| PMID | 33576216 | |
| Literature evidence | The exposure of MCF-7 cells to 1 and 10 mg/ml of P.russeliana leaf extract also led to a significant decrease in cell viability. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Phlomis russeliana | |
| Geographical availability | Native to: Turkey Introduced into: Austria, Czechoslovakia, Great Britain, Ireland, New Zealand South | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | Bcl-2 | |
| Gene or Protein evidence | Bcl-2 gene expression significantly increased in the group exposed to 10 mg/ml of P.ruseliana leaf extract. | |
| Target pathways | Bax-independent apoptotic pathway on MCF-7 cells | |
| IC50 | NA | |
| Potency | NA | |
| Cell line/ mice model | MCF-7 | |
| Additional information | Significantly increases the Bcl-2 gene expression (MCF-7) | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:454047-1 | |
| Safety | NA |