| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-889 | |
| Phytochemical name or plant extracts | Petiolaticin A | |
| PMID | 34717280 | |
| Literature evidence | Additionally, petiolaticin D, 16α,23α-epoxy-3β,20β-dihydroxy-10αH,23βH-cucurbit-5,24-dien-11-one, and 16α,23α-epoxy-3β,20β-dihydroxy-10αH,23βH-cucurbit-5,24-dien-11-one 3-O-β-D-glucopyranoside were tested for their ability to inhibit cell entry of a pseudotyped virus bearing the hemagglutinin envelope protein of a highly pathogenic avian influenza virus. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | NA | |
| Source of phytochemicals or plant Extracts | Elaeocarpus petiolatus | |
| Geographical availability | Andaman Is., Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, Hainan, Jawa, Laos, Lesser Sunda Is., Malaya, Myanmar, Nicobar Is., Sumatera, Thailand, Vietnam | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Pancreatic cancer, Colorectal cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 7.4 μM against MDA-MB-468 9.2 μM against MDA-MB-23 9.3 μM against MCF-7 | |
| Potency | These preliminary biological assays have demonstrated that petiolaticins A and D possess anticancer and antiviral properties, respectively, which warrant for further investigations. | |
| Cell line/ mice model | MDA-MB-468, MDA-MB-231, MCF-7, and SW48 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:833916-1 | |
| Safety | NA |