| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-818 | |
| Phytochemical name or plant extracts | Peganum harmala extract | |
| PMID | 32847047 | |
| Literature evidence | The current findings of this study include a novel comprehensive investigation on the polyphenol composition and anticancer effects of leaf extracts of F. alnus and P. harmala from natural populations in Saudi Arabia. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Peganum harmala | |
| Geographical availability | Afghanistan, Algeria, Bangladesh, Bulgaria, China North-Central, Cyprus, East Aegean Is., East European Russia, Egypt, Greece, India, Inner Mongolia, Iran, Iraq, Italy, Kazakhstan, Kirgizstan, Krym, Kuwait, Lebanon-Syria, Libya, Mongolia, Morocco, North Caucasus, Pakistan, Palestine, Qinghai, Romania, Sardegna, Saudi Arabia, Sinai, South European Russi, Spain, Tadzhikistan, Tibet, Transcaucasus, Tunisia, Turkey, Turkey-in-Europe, Turkmenistan, Tuva, Ukraine, Uzbekistan, West Himalaya, Xinjiang, Yemen, Yugoslavia | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer, Colorectal cancer, Cervical cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 58.64 ± 4.2 µg/mL against MCF-7 | |
| Potency | F. alnus and P. harmala leaf extracts showed cytotoxic effects against Jurkat, MCF-7, HeLa, and HT-29 cancer cells using MTT and flow cytometry assays. | |
| Cell line/ mice model | MCF-7, Jurkat, HeLa, and HT-29 | |
| Additional information | The current findings of this study include a novel comprehensive investigation on the polyphenol composition and anticancer effects of leaf extracts of F. alnus and P. harmala from natural populations in Saudi Arabia. | |
| PubChem ID | NA | |
| Additional PMIDs | 24380828 34194262 32847047 23339401 28352583 33951988 26362768 25054213 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:774545-1 | |
| Safety | NA |