| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1717 | |
| Phytochemical name or plant extracts | Pashanone | |
| PMID | 32433929 | |
| Literature evidence | Flavonoid, stilbene and diarylheptanoid constituents of Persicaria maculosa Gray and cytotoxic activity of the isolated compounds. | |
| IUPAC name | (E)-1-(2,6-dihydroxy-3,4-dimethoxyphenyl)-3-phenylprop-2-en-1-one | |
| Phytochemicals’ class or type of plant extracts | Flavonoid | |
| Source of phytochemicals or plant Extracts | Persicaria maculosa | |
| Geographical availability | Afghanistan, Albania, Algeria, Altay, Amur, Austria, Azores, Baleares, Baltic States, Belarus, Belgium, Bulgaria, Central European Rus, China North-Central, China South-Central, China Southeast, Corse, Czechoslovakia, Denmark, East European Russia, East Himalaya, Egypt, Finland, France, Germany, Great Britain, Greece, Hungary, Inner Mongolia, Iran, Iraq, Ireland, Irkutsk, Italy, Japan, Kazakhstan, Kirgizstan, Korea, Krasnoyarsk, Krym, Laos, Lebanon-Syria, Madeira, Manchuria, Morocco, Nepal, Netherlands, North Caucasus, North European Russi, Northwest European R, Norway, Pakistan, Poland, Portugal, Qinghai, Romania, Sardegna, Saudi Arabia, Sicilia, South European Russi, Spain, Sweden, Switzerland, Tadzhikistan, Transcaucasus, Tunisia, Turkey, Turkey-in-Europe, Turkmenistan, Ukraine, Uzbekistan, Vietnam, West Himalaya, West Siberia, Xinjiang, Yemen, Yugoslavia | |
| Plant parts | Whole plants | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Impedance changes of 4 T1 mouse triple negative breast cancer cells treated with 2′-hydroxy-3′,4′,6′-trimethoxy chalcone (1) and pashanone (2) in concentrations of 10, 20 or 50 μmol/L. | |
| Cell line/ mice model | 4T1 | |
| Additional information | These compounds, identified as pashanone and 5-hydroxy-6,7-dimethoxyflavanone, exhibited potent antifungal activities against various human pathogenic fungi with minimum inhibitory concentration values ranging from 4.0 to >128 μg/ml. | |
| PubChem ID | 6254251 | |
| Additional PMIDs | 27363478 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:695052-1 | |
| Safety | NA |